STATIC - Crohn's Disease




STopping Aminosalicylate Therapy in Inactive Crohn's Disease Study

A group of medication known as 5-ASAs are often used for management of Crohns Disease (CD) and are thought to have an anti-inflammatory effect on the lining of the bowel. 

Generally, they are considered to be safe and inexpensive agents, although rare but serious side effects can occur. 

Unlike Ulcerative colitis, there is little evidence that 5-ASAs are any more effective than dummy treatment (placebo) in maintaining remission for patients with CD, but many doctors still prescribe 5- ASAs in CD. 

This clinical trial will aim to definitively answer the question of whether 5-ASAs should be continued in patients with CD who are in remission. 

It will compare the safety and effectiveness of continuing existing 5-ASA medication versus stopping it. 

The results of the study may have implications for the management of CD worldwide and help to improve evidence-based treatment guidelines and the approach to patient care.

If you are eligible to take part in this trial, you will receive an invitation letter from the practice.